Systemic Effects or Systemic Toxicity

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Term Systemic Effects or Systemic Toxicity
Description Toxic effects as a result of absorption and distribution of a toxicant to a site distant from its entry point.
Definition Systemic Effects or Systemic Toxicity

Toxic effects as a result of absorption and distribution of a toxicant to a site distant from its entry point. Systemic effects are those that require absorption and distribution of the toxicant to a site distant from its entry point, at which point effects are produced. Most chemicals that produce systemic toxicity do not cause a similar degree of toxicity in all organs, but usually demonstrate major toxicity to one or two organs. These are referred to as the target organs of toxicity for that chemical.

References http://www.epa.gov/iris/help_gloss.htm#s
http://rais.ornl.gov/home/glossary.html#L  

 

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